
Depo Provera Lawsuit: Depo Shot Lawsuit & Brain Tumor Claims Explained
What is a Depo-Provera Lawsuit?
Depo Provera has been widely used as a long-acting birth control injection for many years. However, growing concerns about serious health risks, including potential links to brain tumors, have led many individuals to file a Depo Provera lawsuit against drug manufacturers. If you or a loved one experienced severe side effects after using Depo-Provera (the Depo Shot), you may be eligible to seek compensation. We’re here to help you understand your options and take the next step.
The Depo Provera lawsuit centers on allegations that long-term use of the Depo Provera contraceptive injection increases the risk of developing brain tumors, particularly meningiomas. Plaintiffs claim that manufacturers, Pfizer and Prasco Labs, failed to provide adequate warnings to patients and healthcare providers about these risks.
Women who relied on Depo-Provera for birth control allege they were not fully informed of the potential long-term neurological dangers, leading to delayed diagnosis and severe medical consequences. Depo-Provera is an injectable hormonal contraceptive administered once every three months. It contains medroxyprogesterone acetate, a synthetic form of progesterone designed to prevent ovulation and pregnancy.
While effective, Depo Provera has been associated with several side effects, and recent studies have raised concerns about a possible link between prolonged use and brain tumor development, leading to an increase in depo lawsuit filings.
Who is Eligible to File a Claim?
You may be eligible to file an Depo Provera lawsuit if:
- You received Depo-Provera injections for birth control.
- You were diagnosed with a brain tumor, such as meningioma.
- You required surgery, radiation, or long-term treatment.
- You were not adequately warned about the risk of brain tumors.
- A loved one suffered severe complications or passed away after Depo-Provera use.
Depo Provera and Brain Tumor Risk
Medical research has increasingly examined the connection between Depo Provera and brain tumors, especially hormone-sensitive tumors like meningiomas. These tumors can press against the brain or spinal cord, causing serious neurological symptoms
Many lawsuits allege that the hormonal composition of Depo-Provera may promote tumor growth when used over extended periods.
What are the Side Effects of Depo Provera?
A French study found that women who used Depo Provera for over a year had a 5.6 times higher risk of developing meningioma, a type of brain tumor. In addition to this serious concern, the shot has been linked to fertility issues and more common side effects like nausea and headaches.
Here are some of the commonly reported health effects of Depo Provera:
01 - Bone Mineral Density Loss
Using Depo-Provera for long periods has been linked to a significant decrease in bone mineral density (BMD), leading to weakened bones and an increased risk of fractures.
02 - Brain Tumor
Some women have filed lawsuits alleging that long-term use of Depo-Provera contributed to the development of brain tumors, particularly meningiomas.
03 - Menstrual Cycle Changes
Some women reported extremely heavy bleeding, while others experienced complete amenorrhea (no periods).
04 - Bloating and Abdominal Pain
Women using Depo-Provera reported digestive discomfort, bloating, lower abdominal pain, and frequent headaches.
05 - Cardiovascular Risks
Emerging research and user reports have suggested a possible link between long-term use of Depo-Provera and an increased risk of heart disease.
Depo Provera Legal Claims
The Depo Provera lawsuit and individual claims typically allege:
If you’ve suffered harm, you may qualify to file a lawsuit under the following conditions:
Failure to warn users about brain tumor risks.
Defective drug design.
Negligent marketing practices.
Misrepresentation of long-term safety.
Corporate negligence and lack of informed consent.
Depo Provera Legal News: MDL Updates & Litigation Status
Pfizer is currently battling a lawsuit in which more than 1,000 women claim the company knew about the risk and failed to warn patients.
- U.S. District Judge M. Casey Rodgers, who is overseeing about 2,000 Depo-Provera lawsuits, heard oral arguments on Pfizer's federal preemption motion on Sept. 29.
- The judge set the first Depo-Provera trial for Dec. 7, 2026.
- The U.S. Food and Drug Administration (FDA) has approved a label change for Pfizer’s Depo-Provera birth control injection to include a warning about the risk of meningioma, a type of brain tumor affecting the lining of the brain.
What Compensation Can You Get?
The compensation depends on the severity of your condition and how it has impacted your life. Victims with serious, long-term effects such as meningioma may be entitled to higher payouts. Estimated settlement values range from $150,000 for minor injuries to over $1,500,000 for severe cases.
If eligible, you may be able to recover damages such as:
Medical Expenses
Costs of diagnosis, treatment, medication, surgeries, and long-term care.
Lost Wages
Income lost due to time away from work or reduced earning capacity.
Pain and Suffering
Compensation for physical pain, emotional distress, and reduced quality of life.
Future Medical Needs
Projected healthcare expenses if your condition requires ongoing treatment.
Wrongful Death Damages
If a loved one died due to Depo-Provera-related complications, surviving family members may be entitled to funeral costs and additional damages.
Real Stories Behind Lawsuit
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Sandra Somarakis: Sandra used Depo-Provera from 1996 to 2010 and was later diagnosed with meningioma. She underwent radiation therapy to completely remove the tumor.
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Taylor Devorak: Taylor alleges that researchers have found a link between Depo-Provera and a higher incidence of brain tumors known as intracranial meningioma. She is seeking damages for failure to warn, defective design, negligence, and misrepresentation.
How to File an Depo Provera Lawsuit with Connect2Attorney?
Connect2Attorney guides you through the process of filing an Depo Provera lawsuit against the responsible party, in just three simple steps:
Submit a Free Case Review
Share details about your situation so we can understand your claim.
Confirm Eligibility
Our legal team will review your case and let you know if you qualify.
Sign Agreement
If eligible, sign a legal agreement. Your attorney will handle all legal formalities.
Depo Provera Lawsuit Timeline
2025First Half
January
Pfizer agreed to the creation of a multidistrict litigation (MDL) to address the Depo-Provera lawsuits but disagreed with plaintiffs' attorneys on where it should be centralized.
February
A federal judicial panel consolidated 27 cases from eight different districts and transferred them to the Northern District of Florida for pretrial proceedings.
March
The court approved a discovery schedule for five pilot cases, beginning on March 27 and continuing through March 2026.
April
The court set a deadline for generic manufacturers, including Viatris and Greenstone, to formally declare they were not involved in the case.
May
Pfizer produced more than 1 million documents related to Depo-Provera, which were submitted to the court and plaintiffs’ legal teams.
June
Greenstone and Viatris were dismissed from the Depo-Provera litigation, similar to the earlier dismissal of Prasco.
2025Second Half
July
The number of active Depo-Provera lawsuits in federal court reached 550, with over 100 new cases filed in just the past few weeks.
August
Pfizer filed a motion for summary judgment in the Depo-Provera litigation, asking the court to rule in its favor without proceeding to trial.
September
Pfizer claimed the FDA blocked its attempt to add a meningioma warning to the Depo-Provera label after a formal request in 2024.
October
The number of active Depo-Provera lawsuits consolidated in federal court rose to 1,222.
Get Legal Support from Connect2Attorney
You don’t have to face this challenge alone. If Depo-Provera caused serious harm to your health, Connect2Attorney is here to help you:
Any Questions? We Got You
Who is eligible to file a Depo Provera lawsuit?
You may be eligible if you used Depo-Provera (the depo shot) and were later diagnosed with a brain tumor such as meningioma, especially if you were not warned about this risk before using the drug.
What health conditions are linked to Depo-Provera lawsuits?
Most Depo Provera lawsuits focus on meningioma, a type of brain tumor. Claims may involve symptoms such as severe headaches, vision problems, seizures, or the need for surgery or long-term medical care.
What legal claims are being filed in Depo Provera cases?
Claims generally allege failure to warn, inadequate safety disclosures, and negligent marketing. Plaintiffs argue that manufacturers did not properly inform patients about known or potential brain tumor risks.
What compensation may be available in a Depo Provera lawsuit?
Compensation may include medical expenses, lost income, pain and suffering, future treatment costs, and other damages related to the injury. The amount depends on the severity of the condition and individual case details.
How do I start a Depo Provera lawsuit claim?
The first step is to speak with a qualified attorney who can review your medical history and Depo-Provera use. A lawyer can help determine eligibility, file the claim, and guide you through the legal process.

