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Oxbryta Liver Injury Lawsuit: Claims, Side Effects & Legal Updates

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What is Oxbryta Liver Injury Lawsuit?

Recent studies have shown that people taking Oxbryta experienced higher rates of pain episodes called vaso-occlusive crises (VOCs) compared to those who did not take the drug. It has also been linked to liver injuries with long-term use.


If you have suffered an injury caused by Oxbryta and plan to sue Pfizer for your pain, we are here to help you fight for the compensation you deserve.


The Oxbryta Liver Injury Lawsuit involves legal claims brought by patients who suffered liver damage after using Oxbryta, a drug developed to treat sickle cell anemia. These lawsuits allege that Pfizer failed to properly warn patients and doctors about the risk of liver injury and other serious side effects linked to the medication.


The litigation is still in the early stages, and there are currently no official reports on how many lawsuits have been filed against the manufacturer. 


What is Oxbryta? 

Oxbryta (voxelotor) is a medication approved to treat sickle cell disease in adults and children over 12. It works by increasing hemoglobin’s oxygen-carrying capacity, helping reduce the symptoms of sickle cell disease, such as fatigue and anemia

While Oxbryta has improved quality of life for many patients, post-marketing reports have raised concerns about potential liver damage in some individuals. These reports have triggered lawsuits from affected patients.


Who is Eligible to File a Claim?

You may be eligible to file a Hair Relaxer Cancer Lawsuit if:

  • 1. Have a documented liver injury

    Diagnosed with liver damage after starting Oxbryta

    Hospitalization or medical treatment required due to liver complications

  • 2. Used Oxbryta for sickle cell disease

    Prescription records showing use of the drug

  • 3. Experienced significant side effects

    Elevated liver enzymes, jaundice, or other liver-related conditions

Oxbryta Side Effects and Liver Damage Risk Explained

Long-term use of Suboxone can affect more than just teeth. Many patients report additional health problems that impact daily life and well-being. Understanding these risks is important for anyone considering legal action. 

The main other health risks associated with Oxbryta include:

Vaso-Occlusive Crises (VOCs)

Some patients experience severe and sudden pain episodes caused by blocked blood flow in the vessels.

Increased Risk of Death

Studies suggest higher mortality rates among certain patients taking Oxbryta compared to those not using the medication.

Kidney Complications

Prolonged use has been linked to kidney stress and potential long-term kidney damage, requiring ongoing medical monitoring.

Cardiovascular Issues

Some patients have reported increased heart strain and cardiovascular complications during treatment with Oxbryta.

Gastrointestinal Problems

Commonly reported side effects include nausea, vomiting, abdominal pain, and other digestive system discomfort.

Allergic Reactions

Some individuals may experience serious allergic reactions such as rash, swelling, breathing difficulty, or hypersensitivity.

Oxbryta Lawsuit Update: FDA Warnings, Recalls & Case Status

On September 25, 2024, the FDA issued a warning advising doctors to stop prescribing Oxbryta and recommending that patients speak with their healthcare providers about discontinuing the drug. This warning was followed by a voluntary recall after clinical trials revealed an increased risk of vaso-occlusive crises and death. In December 2025, the European Medicines Agency (EMA) confirmed the recall, concluding that the risks of Oxbryta outweighed its benefits for sickle cell patients based on new data showing higher rates of crises and deaths, particularly in children.


The Oxbryta lawsuits are still in the early stages, with at least 18 cases currently pending in federal and state courts. The claims allege that Pfizer failed to properly evaluate the drug’s safety and placed profits above patient well-being. A federal judge has set the first Oxbryta wrongful death case for trial on September 13, 2027.

Oxbryta Lawyers: How to Find the Right Attorney?

Choosing the right attorney is critical for a successful Oxbryta lawsuit. Here’s what to consider:  

Experience with drug injury cases: :Look for lawyers with a proven track record in pharmaceutical litigation.

Knowledge of Oxbryta lawsuits: :Attorneys familiar with the drug’s side effects, FDA warnings, and recent settlements.

Transparent communication: :Clear guidance on fees, case timelines, and expected outcomes.

Oxbryta Settlements & Compensation Overview  

Oxbryta liver injury lawsuits are still in the early stages, making it difficult to predict the exact compensation. However, based on similar pharmaceutical cases, settlements or awards could range from $20,000 to $1 million, depending on the severity of injuries.

Medical Expenses

Coverage for hospital bills, doctor visits, medications, and ongoing treatment related to liver damage.

Pain and Suffering

Compensation for income loss due to illness, hospital stays, or inability to work during recovery.  

Lost wages

Financial recognition for physical pain, emotional distress, and decreased quality of life.  

Legal Costs

Reimbursement for attorney fees and court-related expenses incurred while pursuing the lawsuit.

Punitive damages

In some cases, courts may award additional compensation to punish the manufacturer for negligence or deceptive practices.

How to File a Oxbryta Liver Injury Lawsuit with Connect2Attorney?   

Connect2Attorney guides you through the process of filing a Oxbryta liver injury lawsuit against the responsible party, in just three simple steps:  

Step1

Submit a Free Case Review

Share details about your situation so we can understand your claim.

Step2

Confirm Eligibility

Our legal team will review your case and let you know if you qualify.

Step3

Sign Agreement

If eligible, sign a legal agreement. Your attorney will handle all legal formalities.

Oxbryta Liver Injury Lawsuit Timeline  

2026First Half

January

Settlement discussions and negotiations have progressed for patients alleging serious injuries linked to Oxbryta, as lawsuits continue to develop against Pfizer and Global Blood Therapeutics.

Get Legal Support from Connect2Attorney

You’re not alone in this fight. If Oxbryta has caused you liver injury or any other health problem, Connect2Attorney can help you:

Any Questions? We Got You

What is Oxbryta?

Oxbryta is a prescription medication used to treat sickle cell disease. It works by improving the ability of red blood cells to carry oxygen and reducing complications related to sickle cell anemia.

What are the risks of taking Oxbryta?

Reported risks of Oxbryta include liver injury, severe pain crises, worsening anemia symptoms, and potential complications affecting the kidneys and heart. Some patients may require additional medical treatment due to these side effects.

Who can file an Oxbryta lawsuit?

Patients who suffered liver damage, severe complications, or other serious side effects after using Oxbryta may be eligible to file a lawsuit. Families of individuals who experienced severe harm or death may also qualify for wrongful death claims.

Are Oxbryta lawsuits ongoing?

Yes. Oxbryta lawsuits are currently in the early stages, and additional claims are expected as more patients come forward and medical evidence continues to develop.

What compensation can be sought in an Oxbryta lawsuit?

Compensation may include medical expenses, lost wages, ongoing treatment costs, pain and suffering, and in some cases punitive damages depending on the severity of injuries and supporting evidence.

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